| 27 Aug 10 | V. Obinna Victor Obinna |  InternazionaleINT | → |  West Ham UnitedWHU | Loan |
| 27 Aug 10 | V. Obinna Victor Obinna | InternazionaleINT | → | West Ham UnitedWHU | Loan |
| 13 Aug 10 | M. Balotelli Mario Balotelli | InternazionaleINT | → |  Manchester CityMNC | Undisclosed |
| 13 Aug 10 | M. Balotelli Mario Balotelli | InternazionaleINT | → | Manchester CityMNC | Undisclosed |
| 28 Jul 10 | R. Krhin Rene Krhin | InternazionaleINT | → |  BolognaBOL | Free |
| 28 Jul 10 | Amantino Mancini |  AC MilanMIL | → | InternazionaleINT | Free |
| 28 Jul 10 | M. Fossati Marco Fossati | InternazionaleINT | → | AC MilanMIL | Free |
| 25 Jul 10 | D. Faraoni Davide Faraoni |  LazioLAZ | → | InternazionaleINT | Free |
| 25 Jul 10 | R. Quaresma Ricardo Quaresma | InternazionaleINT | → |  BesiktasBES | Free |
| 25 Jul 10 | Francesco Toldo | InternazionaleINT | → | RXXRetiroRetiro | Free |
| 25 Jul 10 | P. Coutinho Philippe Coutinho |  Vasco da GamaVAS | → | InternazionaleINT | Free |
| 25 Jul 10 | M. Arnautovic Marko Arnautovic | InternazionaleINT | → |  Werder BremenWER | Free |
| 25 Jul 10 | J. Biabiany Jonathan Biabiany |  ParmaPAR | → | InternazionaleINT | Free |
| 25 Jul 10 | L. Castellazzi Luca Castellazzi |  SampdoriaSAM | → | InternazionaleINT | Free |
| 25 Jul 10 | P. Coutinho Philippe Coutinho | Vasco da GamaVAS | → | InternazionaleINT | Free |
| 25 Jul 10 | M. Destro Mattia Destro | InternazionaleINT | → |  GenoaGEN | Free |
| 25 Jul 10 | Giulio Donati | InternazionaleINT | → |  LecceLEC | Free |
| 25 Jul 10 | M. Arnautovic Marko Arnautovic | InternazionaleINT | → | Werder BremenWER | Free |
| 26 Jun 10 | V. Obinna Victor Obinna |  MálagaMCF | → | InternazionaleINT | Loan |
| 26 Jun 10 | V. Obinna Victor Obinna | MálagaMCF | → | InternazionaleINT | Loan |
| 08 Jan 10 | P. Vieira Patrick Vieira | InternazionaleINT | → | Manchester CityMNC | Free |
| 08 Jan 10 | P. Vieira Patrick Vieira | InternazionaleINT | → | Manchester CityMNC | Free |