| 31 Aug 21 | M. Cucurella Marc Cucurella |  GetafeGET | → |  Brighton & Hove AlbionBHA | Undisclosed |
| 31 Aug 21 | L. Dendoncker Lars Dendoncker | Brighton & Hove AlbionBHA | → |  St JohnstoneSTJO | Loan |
| 31 Aug 21 | M. Caicedo Moises Caicedo | Brighton & Hove AlbionBHA | → |  BeerschotBEER | Loan |
| 31 Aug 21 | A. Sima Abdallah Sima | SPXSlavia PragueSlavia Prague | → | Brighton & Hove AlbionBHA | Undisclosed |
| 31 Aug 21 | M. Cucurella Marc Cucurella | GetafeGET | → | Brighton & Hove AlbionBHA | Undisclosed |
| 31 Aug 21 | A. Sima Abdallah Sima | Brighton & Hove AlbionBHA | → |  Stoke CitySTK | Loan |
| 31 Aug 21 | R. Khadra Reda Khadra | Brighton & Hove AlbionBHA | → |  Blackburn RoversBLK | Loan |
| 31 Aug 21 | L. Dendoncker Lars Dendoncker | Brighton & Hove AlbionBHA | → | St JohnstoneSTJO | Loan |
| 31 Aug 21 | A. Sima Abdallah Sima | Brighton & Hove AlbionBHA | → | Stoke CitySTK | Loan |
| 31 Aug 21 | R. Khadra Reda Khadra | Brighton & Hove AlbionBHA | → | Blackburn RoversBLK | Loan |
| 30 Aug 21 | C. Walton Christian Walton | Brighton & Hove AlbionBHA | → |  Ipswich TownIPS | Loan |
| 30 Aug 21 | A. Zeqiri Andi Zeqiri | Brighton & Hove AlbionBHA | → |  FC AugsburgAUG | Loan |
| 30 Aug 21 | A. Zeqiri Andi Zeqiri | Brighton & Hove AlbionBHA | → | FC AugsburgAUG | Loan |
| 29 Aug 21 | J. van Hecke Jan Paul van Hecke | Brighton & Hove AlbionBHA | → | Blackburn RoversBLK | Loan |
| 29 Aug 21 | J. van Hecke Jan Paul van Hecke | Brighton & Hove AlbionBHA | → | Blackburn RoversBLK | Loan |
| 28 Aug 21 | M. Karbownik Michal Karbownik | Brighton & Hove AlbionBHA | → |  OlympiakosOLY | Loan |
| 27 Aug 21 | J. Molumby Jayson Molumby | Brighton & Hove AlbionBHA | → |  West Bromwich AlbionWBA | Loan |
| 27 Aug 21 | J. Molumby Jayson Molumby | Brighton & Hove AlbionBHA | → | West Bromwich AlbionWBA | Loan |
| 26 Aug 21 | P. Tau Percy Tau | Brighton & Hove AlbionBHA | → | AAXAl AhlyAl Ahly | Undisclosed |
| 23 Aug 21 | F. Andone Florin Andone | Brighton & Hove AlbionBHA | → |  CádizCAD | Loan |
| 23 Aug 21 | F. Andone Florin Andone | Brighton & Hove AlbionBHA | → | CádizCAD | Loan |
| 10 Aug 21 | L. Ostigard Leo Ostigard | Brighton & Hove AlbionBHA | → | Stoke CitySTK | Loan |
| 10 Aug 21 | K. Mitoma Kaoru Mitoma |  Kawasaki FrontaleKAW | → | Brighton & Hove AlbionBHA | Undisclosed |
| 10 Aug 21 | K. Mitoma Kaoru Mitoma | Brighton & Hove AlbionBHA | → |  Union St.-GilloiseUSG | Loan |
| 10 Aug 21 | L. Ostigard Leo Ostigard | Brighton & Hove AlbionBHA | → | Stoke CitySTK | Loan |
| 30 Jul 21 | B. White Ben White | Brighton & Hove AlbionBHA | → |  ArsenalARS | Undisclosed |
| 17 Jul 21 | A. Jahanbakhsh Alireza Jahanbakhsh | Brighton & Hove AlbionBHA | → |  Feyenoord RotterdamFEY | Undisclosed |
| 17 Jul 21 | A. Jahanbakhsh Alireza Jahanbakhsh | Brighton & Hove AlbionBHA | → | Feyenoord RotterdamFEY | Undisclosed |
| 16 Jul 21 | K. Scherpen Kjell Scherpen |  Ajax AmsterdamAJA | → | Brighton & Hove AlbionBHA | Undisclosed |
| 16 Jul 21 | K. Scherpen Kjell Scherpen | Ajax AmsterdamAJA | → | Brighton & Hove AlbionBHA | Undisclosed |
| 15 Jul 21 | C. Rushworth Carl Rushworth | Brighton & Hove AlbionBHA | → |  WalsallWAL | Loan |
| 13 Jul 21 | M. Clarke Matthew Clarke | Brighton & Hove AlbionBHA | → | West Bromwich AlbionWBA | Loan |
| 13 Jul 21 | J. Weir Jensen Weir | Brighton & Hove AlbionBHA | → |  Cambridge UnitedCAMB | Loan |
| 13 Jul 21 | M. Clarke Matthew Clarke | Brighton & Hove AlbionBHA | → | West Bromwich AlbionWBA | Loan |
| 12 Jul 21 | M. Ryan Mat Ryan | Brighton & Hove AlbionBHA | → |  Real SociedadRSO | Undisclosed |
| 12 Jul 21 | M. Ryan Mat Ryan | Brighton & Hove AlbionBHA | → | Real SociedadRSO | Undisclosed |
| 11 Jul 21 | R. Yapi Romaric Yapi | Brighton & Hove AlbionBHA | → |  VitesseVIT | Undisclosed |
| 11 Jul 21 | R. Yapi Romaric Yapi | Brighton & Hove AlbionBHA | → | VitesseVIT | Undisclosed |
| 09 Jul 21 | V. Gyökeres Viktor Gyökeres | Brighton & Hove AlbionBHA | → |  Coventry CityCOV | Undisclosed |
| 09 Jul 21 | V. Gyökeres Viktor Gyökeres | Brighton & Hove AlbionBHA | → | Coventry CityCOV | Undisclosed |
| 07 Jul 21 | R. Longman Ryan Longman | Brighton & Hove AlbionBHA | → |  Hull CityHUL | Loan |
| 07 Jul 21 | R. Longman Ryan Longman | Brighton & Hove AlbionBHA | → | Hull CityHUL | Loan |
| 06 Jul 21 | E. Mwepu Enock Mwepu |  FC SalzburgSLZ | → | Brighton & Hove AlbionBHA | Undisclosed |
| 02 Jul 21 | Bernardo | Brighton & Hove AlbionBHA | → | FC SalzburgSLZ | Undisclosed |
| 02 Jul 21 | Jeremy Sarmiento |  BenficaBEN | → | Brighton & Hove AlbionBHA | Undisclosed |
| 01 Jul 21 | D. Propper Davy Propper | Brighton & Hove AlbionBHA | → |  PSV EindhovenPSV | Undisclosed |
| 01 Jul 21 | J. Mlakar Jan Mlakar | Brighton & Hove AlbionBHA | → | HSXHajduk SplitHajduk Split | Undisclosed |
| 01 Jul 21 | T. Jenks Teddy Jenks | Brighton & Hove AlbionBHA | → |  AberdeenABER | Loan |
| 01 Jul 21 | A. Cochrane Alex Cochrane | Brighton & Hove AlbionBHA | → |  Heart of MidlothianHOM | Loan |
| 01 Jul 21 | T. Jenks Teddy Jenks | Brighton & Hove AlbionBHA | → | AberdeenABER | Loan |
| 01 Jul 21 | D. Propper Davy Propper | Brighton & Hove AlbionBHA | → | PSV EindhovenPSV | Undisclosed |
| 01 Jul 21 | A. Cochrane Alex Cochrane | Brighton & Hove AlbionBHA | → | Heart of MidlothianHOM | Loan |
| 01 Feb 21 | M. Sanders Max Sanders | Brighton & Hove AlbionBHA | → |  Colchester UnitedCOL | Undisclosed |
| 01 Feb 21 | G. Murray Glenn Murray | Brighton & Hove AlbionBHA | → |  Nottingham ForestFOR | Undisclosed |
| 01 Feb 21 | M. Caicedo Moises Caicedo |  Independiente del ValleIDV | → | Brighton & Hove AlbionBHA | Undisclosed |
| 01 Feb 21 | G. Murray Glenn Murray | Brighton & Hove AlbionBHA | → | Nottingham ForestFOR | Undisclosed |
| 22 Jan 21 | M. Ryan Mat Ryan | Brighton & Hove AlbionBHA | → | ArsenalARS | Loan |
| 19 Jan 21 | Bernardo | Brighton & Hove AlbionBHA | → | FC SalzburgSLZ | Loan |
| 18 Jan 21 | W. O'Hora Warren O'Hora | Brighton & Hove AlbionBHA | → |  Milton Keynes DonsMKD | Undisclosed |
| 15 Jan 21 | V. Gyökeres Viktor Gyökeres | Brighton & Hove AlbionBHA | → | Coventry CityCOV | Loan |
| 15 Jan 21 | V. Gyökeres Viktor Gyökeres | Brighton & Hove AlbionBHA | → | Coventry CityCOV | Loan |
| 05 Jan 21 | J. Molumby Jayson Molumby | Brighton & Hove AlbionBHA | → |  Preston North EndPNE | Loan |
| 05 Jan 21 | J. Molumby Jayson Molumby | Brighton & Hove AlbionBHA | → | Preston North EndPNE | Loan |