| 30 Aug 22 | A. Okoflex Armstrong Okoflex |  West Ham UnitedWHU | → |  Swansea CitySWA | Loan |
| 29 Aug 22 | L. Paquetá Lucas Paquetá |  LyonLYON | → | West Ham UnitedWHU | Undisclosed |
| 26 Aug 22 | A. Odubeko Ademipo Odubeko | West Ham UnitedWHU | → |  Port ValePTV | Loan |
| 26 Aug 22 | D. Chesters Daniel Chesters | West Ham UnitedWHU | → |  Colchester UnitedCOL | Loan |
| 23 Aug 22 | Emerson |  ChelseaCHE | → | West Ham UnitedWHU | Undisclosed |
| 21 Aug 22 | N. Trott Nathan Trott | West Ham UnitedWHU | → | VXXVejleVejle | Loan |
| 18 Aug 22 | T. Nevers Thierry Nevers | West Ham UnitedWHU | → |  Newport CountyNEW | Loan |
| 17 Aug 22 | T. Kehrer Thilo Kehrer |  Paris Saint-Germain PSG | → | West Ham UnitedWHU | Undisclosed |
| 14 Aug 22 | J. Anang Joseph Anang | West Ham UnitedWHU | → |  Derby CountyDER | Loan |
| 11 Aug 22 | N. Vlasic Nikola Vlasic | West Ham UnitedWHU | → |  TorinoTOR | Loan |
| 10 Aug 22 | I. Diop Issa Diop | West Ham UnitedWHU | → |  FulhamFUL | Undisclosed |
| 05 Aug 22 | M. Cornet Maxwel Cornet |  BurnleyBUR | → | West Ham UnitedWHU | Undisclosed |
| 02 Aug 22 | A. Masuaku Arthur Masuaku | West Ham UnitedWHU | → |  BesiktasBES | Loan |
| 26 Jul 22 | G. Scamacca Gianluca Scamacca |  SassuoloSAS | → | West Ham UnitedWHU | Undisclosed |
| 19 Jul 22 | S. Perkins Sonny Perkins | West Ham UnitedWHU | → |  Leeds UnitedLEE | Undisclosed |
| 15 Jul 22 | A. Alese Ajibola Alese | West Ham UnitedWHU | → |  SunderlandSUN | Undisclosed |
| 07 Jul 22 | F. Downes Flynn Downes | Swansea CitySWA | → | West Ham UnitedWHU | Undisclosed |
| 01 Jul 22 | N. Aguerd Nayef Aguerd |  Stade RennaisREN | → | West Ham UnitedWHU | Undisclosed |
| 01 Jul 22 | A. Areola Alphonse Areola | Paris Saint-Germain PSG | → | West Ham UnitedWHU | Undisclosed |
| 31 Jan 22 | F. Alves Frederik Alves | West Ham UnitedWHU | → |  BrøndbyBRO | Undisclosed |
| 27 Jan 22 | A. Odubeko Ademipo Odubeko | West Ham UnitedWHU | → |  Doncaster RoversDON | Loan |
| 18 Jan 22 | C. Coventry Conor Coventry | West Ham UnitedWHU | → |  Milton Keynes DonsMKD | Loan |