| 20 Aug 19 | T. Jedvaj Tin Jedvaj |  Bayer LeverkusenLEV | → |  FC AugsburgAUG | Loan |
| 30 Jul 19 | N. Amiri Nadiem Amiri |  TSG HoffenheimHOF | → | Bayer LeverkusenLEV | Undisclosed |
| 03 Jul 19 | D. Kohr Dominik Kohr | Bayer LeverkusenLEV | → |  Eintracht FrankfurtSGE | Undisclosed |
| 01 Jul 19 | M. Diaby Moussa Diaby |  Paris Saint-Germain PSG | → | Bayer LeverkusenLEV | Undisclosed |
| 01 Jul 19 | M. Hummels Mats Hummels | Bayer LeverkusenLEV | → |  Borussia DortmundDOR | Undisclosed |
| 01 Jul 19 | S. Schreck Sam Schreck | Bayer LeverkusenLEV | → |  FC GroningenGRO | Undisclosed |
| 01 Jul 19 | D. Sinkgraven Daley Sinkgraven |  Ajax AmsterdamAJA | → | Bayer LeverkusenLEV | Undisclosed |
| 01 Jul 19 | T. Kirschbaum Thorsten Kirschbaum | Bayer LeverkusenLEV | → |  VVV-VenloVVV | Free |
| 01 Jul 19 | T. Kirschbaum Thorsten Kirschbaum | Bayer LeverkusenLEV | → | VVV-VenloVVV | Free |
| 01 Jul 19 | J. Brandt Julian Brandt | Bayer LeverkusenLEV | → | Borussia DortmundDOR | Undisclosed |
| 01 Jul 19 | K. Demirbay Kerem Demirbay | TSG HoffenheimHOF | → | Bayer LeverkusenLEV | Undisclosed |
| 01 Jul 19 | S. Schreck Sam Schreck | Bayer LeverkusenLEV | → | FC GroningenGRO | Undisclosed |
| 01 Jul 19 | D. Sinkgraven Daley Sinkgraven | Ajax AmsterdamAJA | → | Bayer LeverkusenLEV | Undisclosed |
| 01 Jul 19 | M. Diaby Moussa Diaby | Paris Saint-Germain PSG | → | Bayer LeverkusenLEV | Undisclosed |
| 23 Jan 19 | Tomasz Kucz | Bayer LeverkusenLEV | → | DSXDunajska StredaDunajska Streda | Loan |
| 22 Jan 19 | J. Bednarczyk Jakub Bednarczyk | Bayer LeverkusenLEV | → |  St PauliSTP | Undisclosed |