| 30 Aug 17 | F. Passlack Felix Passlack |  Borussia DortmundDOR | → |  TSG HoffenheimHOF | Loan |
| 30 Aug 17 | J. Toljan Jeremy Toljan | TSG HoffenheimHOF | → | Borussia DortmundDOR | Undisclosed |
| 14 Aug 17 | M. Terrazzino Marco Terrazzino | TSG HoffenheimHOF | → |  SC FreiburgFREI | Undisclosed |
| 10 Aug 17 | R. Canouse Russell Canouse | TSG HoffenheimHOF | → |  D.C. UnitedDC | Undisclosed |
| 10 Aug 17 | R. Canouse Russell Canouse | TSG HoffenheimHOF | → | D.C. UnitedDC | Undisclosed |
| 22 Jul 17 | F. Schär Fabian Schär | TSG HoffenheimHOF | → |  Deportivo La CoruñaDEP | Undisclosed |
| 22 Jul 17 | F. Schär Fabian Schär | TSG HoffenheimHOF | → | Deportivo La CoruñaDEP | Undisclosed |
| 14 Jul 17 | S. Gnabry Serge Gnabry |  Bayern MunichMUN | → | TSG HoffenheimHOF | Loan |
| 08 Jul 17 | N. Schulz Nico Schulz |  Borussia MonchengladbachMON | → | TSG HoffenheimHOF | Undisclosed |
| 06 Jul 17 | B. Gimber Benedikt Gimber | TSG HoffenheimHOF | → | JRXJahn RegensburgJahn Regensburg | Loan |
| 04 Jul 17 | A. Colak Antonio-Mirko Colak | TSG HoffenheimHOF | → |  FC Ingolstadt 04ING | Loan |
| 01 Jul 17 | B. Atik Baris Atik | TSG HoffenheimHOF | → |  KaiserslauternFCK | Loan |
| 01 Jul 17 | J. Hoogma Justin Hoogma |  Heracles AlmeloHER | → | TSG HoffenheimHOF | Undisclosed |
| 01 Jul 17 | Danny Da Costa |  Bayer LeverkusenLEV | → | TSG HoffenheimHOF | Undisclosed |
| 01 Jul 17 | J. Hoogma Justin Hoogma | Heracles AlmeloHER | → | TSG HoffenheimHOF | Undisclosed |
| 01 Jul 17 | H. Nordtveit Håvard Nordtveit |  West Ham UnitedWHU | → | TSG HoffenheimHOF | Undisclosed |
| 01 Jul 17 | N. Rapp Nicolai Rapp | TSG HoffenheimHOF | → |  FC Erzgebirge AueERZ | Undisclosed |
| 01 Jul 17 | N. Süle Niklas Süle | TSG HoffenheimHOF | → | Bayern MunichMUN | Undisclosed |
| 01 Jul 17 | F. Grillitsch Florian Grillitsch |  Werder BremenWER | → | TSG HoffenheimHOF | Free |
| 01 Jul 17 | S. Rudy Sebastian Rudy | TSG HoffenheimHOF | → | Bayern MunichMUN | Free |
| 01 Jul 17 | P. Schwegler Pirmin Schwegler | TSG HoffenheimHOF | → |  Hannover 96HAN | Free |
| 01 Jul 17 | D. Soares Danilo Soares | TSG HoffenheimHOF | → |  VfL BochumBOC | Free |
| 01 Jul 17 | R. Zulj Robert Zulj |  SpVgg Greuther FurthFUR | → | TSG HoffenheimHOF | Free |
| 01 Jul 17 | H. Nordtveit Håvard Nordtveit | West Ham UnitedWHU | → | TSG HoffenheimHOF | Undisclosed |
| 31 Jan 17 | M. Maric Marko Maric | TSG HoffenheimHOF | → | Hannover 96HAN | Loan |
| 30 Jan 17 | E. Vargas Eduardo Vargas | TSG HoffenheimHOF | → |  Tigres UANLUANL | Undisclosed |
| 30 Jan 17 | E. Vargas Eduardo Vargas | TSG HoffenheimHOF | → | Tigres UANLUANL | Undisclosed |
| 27 Jan 17 | B. Gimber Benedikt Gimber | TSG HoffenheimHOF | → |  Karlsruher SCKAR | Loan |
| 27 Jan 17 | B. Atik Baris Atik | TSG HoffenheimHOF | → |  SK Sturm GrazSTG | Loan |
| 20 Jan 17 | J. Ponce Junior Ponce | TSG HoffenheimHOF | → | UXXUSMPUSMP | Undisclosed |
| 12 Jan 17 | K. Jin-Su Kim Jin-Su | TSG HoffenheimHOF | → | JXXJeonbukJeonbuk | Undisclosed |