| 12 Sept 22 | D. Costa Diego Costa | XXX | → |  Wolverhampton WanderersWOL | Free |
| 01 Sept 22 | B. Traore Boubacar Traore |  MetzMETZ | → | Wolverhampton WanderersWOL | Loan |
| 01 Sept 22 | C. Marques Christian Marques | Wolverhampton WanderersWOL | → |  Forest Green RoversFGR | Loan |
| 01 Sept 22 | W. Boly Willy Boly | Wolverhampton WanderersWOL | → |  Nottingham ForestNFO | Undisclosed |
| 01 Sept 22 | B. Traore Boubacar Traore | MetzMETZ | → | Wolverhampton WanderersWOL | Undisclosed |
| 01 Sept 22 | L. Dendoncker Leander Dendoncker | Wolverhampton WanderersWOL | → |  Aston VillaAVL | Undisclosed |
| 31 Aug 22 | S. Kalajdzic Sasa Kalajdzic |  VfB StuttgartVFB | → | Wolverhampton WanderersWOL | Undisclosed |
| 29 Aug 22 | P. Cutrone Patrick Cutrone | Wolverhampton WanderersWOL | → |  ComoCOMO | Undisclosed |
| 29 Aug 22 | L. Cundle Luke Cundle | Wolverhampton WanderersWOL | → |  Swansea CitySWA | Loan |
| 23 Aug 22 | B. Jordão Bruno Jordão | Wolverhampton WanderersWOL | → |  Santa ClaraSCL | Loan |
| 19 Aug 22 | M. Gibbs-White Morgan Gibbs-White | Wolverhampton WanderersWOL | → | Nottingham ForestNFO | Undisclosed |
| 19 Aug 22 | J. O'Shaughnessy Joseph O'Shaughnessy | Wolverhampton WanderersWOL | → |  Bradford CityBRD | Loan |
| 17 Aug 22 | M. Nunes Matheus Nunes |  Sporting CPSCP | → | Wolverhampton WanderersWOL | 45000000 |
| 08 Aug 22 | G. Guedes Goncalo Guedes |  ValenciaVAL | → | Wolverhampton WanderersWOL | Undisclosed |
| 08 Aug 22 | C. Coady Conor Coady | Wolverhampton WanderersWOL | → |  EvertonEVE | Loan |
| 29 Jul 22 | N. Lonwijk Nigel Lonwijk | Wolverhampton WanderersWOL | → |  Plymouth ArgylePLY | Loan |
| 28 Jul 22 | T. Corbeanu Theo Corbeanu | Wolverhampton WanderersWOL | → |  BlackpoolBLP | Loan |
| 19 Jul 22 | Fábio Silva | Wolverhampton WanderersWOL | → |  AnderlechtAND | Loan |
| 14 Jul 22 | T. Perry Taylor Perry | Wolverhampton WanderersWOL | → |  Cheltenham TownCHL | Loan |
| 12 Jul 22 | N. Collins Nathan Collins |  BurnleyBUR | → | Wolverhampton WanderersWOL | Undisclosed |
| 09 Jul 22 | M. Shabani Meritan Shabani | Wolverhampton WanderersWOL | → |  GrasshoppersGCZ | Undisclosed |
| 09 Jul 22 | R. Dadachov Renat Dadachov | Wolverhampton WanderersWOL | → | GrasshoppersGCZ | Undisclosed |
| 08 Jul 22 | L. Richardson Lewis Richardson | Wolverhampton WanderersWOL | → |  Harrogate TownHAR | Loan |
| 08 Jul 22 | L. Richardson Lewis Richardson | Wolverhampton WanderersWOL | → | Harrogate TownHAR | Loan |
| 05 Jul 22 | D. Sanderson Dion Sanderson | Wolverhampton WanderersWOL | → |  Birmingham CityBIR | Loan |
| 02 Jul 22 | Leon Chiwome |  AFC WimbledonWIM | → | Wolverhampton WanderersWOL | Undisclosed |
| 01 Jul 22 | F. Marçal Fernando Marçal | Wolverhampton WanderersWOL | → |  BotafogoBOT | Free |
| 01 Jul 22 | R. Vinagre Ruben Vinagre | Wolverhampton WanderersWOL | → | Sporting CPSCP | Undisclosed |
| 01 Jul 22 | H. Hee-Chan Hwang Hee-Chan |  RB LeipzigRBL | → | Wolverhampton WanderersWOL | Undisclosed |
| 01 Jul 22 | K. Hoever Ki-Jana Hoever | Wolverhampton WanderersWOL | → |  PSV EindhovenPSV | Loan |
| 01 Jul 22 | R. Giles Ryan John Giles | Wolverhampton WanderersWOL | → |  MiddlesbroughMID | Loan |
| 01 Jul 22 | R. Saïss Romain Saïss | Wolverhampton WanderersWOL | → |  BesiktasBES | Free |
| 31 Jan 22 | R. Giles Ryan John Giles | Wolverhampton WanderersWOL | → |  Blackburn RoversBLK | Loan |
| 31 Jan 22 | B. Jordão Bruno Jordão | Wolverhampton WanderersWOL | → | GrasshoppersGCZ | Loan |
| 29 Jan 22 | A. Traoré Adama Traoré | Wolverhampton WanderersWOL | → |  BarcelonaBAR | Loan |
| 28 Jan 22 | J. Sang-Bin Jeong Sang-Bin | Wolverhampton WanderersWOL | → | GrasshoppersGCZ | Loan |
| 28 Jan 22 | J. Sang-Bin Jeong Sang-Bin | SBXSuwon BluewingsSuwon Bluewings | → | Wolverhampton WanderersWOL | Undisclosed |
| 28 Jan 22 | A. Samuels Austin Samuels | Wolverhampton WanderersWOL | → |  Inverness Caledonian ThistleICT | Undisclosed |
| 25 Jan 22 | D. Sanderson Dion Sanderson | Wolverhampton WanderersWOL | → |  Queens Park RangersQPR | Loan |
| 20 Jan 22 | H. Kawabe Hayao Kawabe | Wolverhampton WanderersWOL | → | GrasshoppersGCZ | Loan |
| 20 Jan 22 | L. Campana Leonardo Campana | Wolverhampton WanderersWOL | → |  Inter Miami CFMIA | Loan |
| 17 Jan 22 | Chiquinho |  EstorilEST | → | Wolverhampton WanderersWOL | Undisclosed |
| 15 Jan 22 | L. Matheson Luke Matheson | Wolverhampton WanderersWOL | → |  Scunthorpe UnitedSCU | Loan |
| 07 Jan 22 | T. Corbeanu Theo Corbeanu | Wolverhampton WanderersWOL | → |  Milton Keynes DonsMKD | Loan |
| 05 Jan 22 | H. Kawabe Hayao Kawabe | GrasshoppersGCZ | → | Wolverhampton WanderersWOL | Undisclosed |