| 11 Sept 25 | A. Onana André Onana |  Manchester UnitedMAN | → |  TrabzonsporTRAB | Loan |
| 01 Sept 25 | H. Amass Harry Amass | Manchester UnitedMAN | → |  Sheffield WednesdaySHW | Loan |
| 01 Sept 25 | R. Højlund Rasmus Højlund | Manchester UnitedMAN | → |  NapoliNAP | Loan |
| 01 Sept 25 | S. Lammens Senne Lammens |  AntwerpANT | → | Manchester UnitedMAN | Undisclosed |
| 01 Sept 25 | J. Sancho Jadon Sancho | Manchester UnitedMAN | → |  Aston VillaAVL | Loan |
| 01 Sept 25 | E. Ennis Ethan Ennis | Manchester UnitedMAN | → |  Fleetwood TownFLE | Loan |
| 30 Aug 25 | A. Garnacho Alejandro Garnacho | Manchester UnitedMAN | → |  ChelseaCHE | Undisclosed |
| 15 Aug 25 | T. Collyer Toby Collyer | Manchester UnitedMAN | → |  West Bromwich AlbionWBA | Loan |
| 09 Aug 25 | B. Sesko Benjamin Sesko |  RB LeipzigRBL | → | Manchester UnitedMAN | Undisclosed |
| 01 Aug 25 | J. Moorhouse Jack Moorhouse | Manchester UnitedMAN | → |  Leyton OrientLEY | Loan |
| 01 Aug 25 | E. Wheatley Ethan Wheatley | Manchester UnitedMAN | → |  Northampton TownNHT | Loan |
| 28 Jul 25 | R. Vítek Radek Vítek | Manchester UnitedMAN | → |  Bristol CityBRC | Loan |
| 23 Jul 25 | M. Rashford Marcus Rashford | Manchester UnitedMAN | → |  BarcelonaBAR | Loan |
| 22 Jul 25 | E. Harrison Elyh Harrison | Manchester UnitedMAN | → |  Shrewsbury TownSHR | Loan |
| 21 Jul 25 | B. Mbeumo Bryan Mbeumo |  BrentfordBRE | → | Manchester UnitedMAN | Undisclosed |
| 19 Jul 25 | J. Hugill Joe Hugill | Manchester UnitedMAN | → |  BarnetBAR | Loan |
| 17 Jul 25 | D. Gore Daniel Gore | Manchester UnitedMAN | → |  Rotherham UnitedROT | Loan |
| 10 Jul 25 | S. Aljofree Sonny Aljofree | Manchester UnitedMAN | → |  Notts CountyNOTT | Loan |
| 05 Jul 25 | D. León Diego León | CPXCerro PorteñoCerro Porteño | → | Manchester UnitedMAN | Undisclosed |
| 16 Jun 25 | M. Cunha Matheus Cunha |  Wolverhampton WanderersWOL | → | Manchester UnitedMAN | Undisclosed |
| 04 Feb 25 | T. Malacia Tyrell Malacia | Manchester UnitedMAN | → |  PSV EindhovenPSV | Loan |
| 03 Feb 25 | S. Mather Sam Mather | Manchester UnitedMAN | → |  Tranmere RoversTRN | Loan |
| 03 Feb 25 | L. Jackson Louis Jackson | Manchester UnitedMAN | → | Tranmere RoversTRN | Loan |
| 02 Feb 25 | M. Rashford Marcus Rashford | Manchester UnitedMAN | → | Aston VillaAVL | Loan |
| 02 Feb 25 | P. Dorgu Patrick Dorgu |  LecceLEC | → | Manchester UnitedMAN | Undisclosed |
| 01 Feb 25 | A. Heaven Ayden Heaven |  ArsenalARS | → | Manchester UnitedMAN | Undisclosed |
| 31 Jan 25 | D. Gore Daniel Gore | Manchester UnitedMAN | → | Rotherham UnitedROT | Loan |
| 25 Jan 25 | Antony | Manchester UnitedMAN | → |  Real BetisBET | Loan |
| 24 Jan 25 | E. Wheatley Ethan Wheatley | Manchester UnitedMAN | → |  WalsallWAL | Loan |
| 10 Jan 25 | E. Ennis Ethan Ennis | Manchester UnitedMAN | → |  Doncaster RoversDON | Loan |