| 01 Sept 22 | L. Mbete Luke Mbete |  Manchester CityMNC | → |  Huddersfield TownHUD | Loan |
| 01 Sept 22 | M. Moreno Marlos Moreno | Manchester CityMNC | → |  TroyesTRY | Undisclosed |
| 01 Sept 22 | J. Larios Juan Larios | Manchester CityMNC | → |  SouthamptonSOU | Undisclosed |
| 01 Sept 22 | S. Edozie Samuel Edozie | Manchester CityMNC | → | SouthamptonSOU | Undisclosed |
| 01 Sept 22 | M. Akanji Manuel Akanji |  Borussia DortmundDOR | → | Manchester CityMNC | Undisclosed |
| 31 Aug 22 | A. Palaversa Ante Palaversa | Manchester CityMNC | → | TroyesTRY | Undisclosed |
| 18 Aug 22 | L. Delap Liam Delap | Manchester CityMNC | → |  Stoke CitySTK | Loan |
| 17 Aug 22 | I. Kaboré Issa Kaboré | Manchester CityMNC | → |  MarseilleOLM | Loan |
| 16 Aug 22 | S. Gómez Sergio Gómez |  AnderlechtAND | → | Manchester CityMNC | Undisclosed |
| 14 Aug 22 | N. Ferraresi Nahuel Ferraresi | Manchester CityMNC | → |  São PauloSAO | Loan |
| 13 Aug 22 | Kayky Chagas | Manchester CityMNC | → |  Paços de FerreiraPFC | Loan |
| 05 Aug 22 | N. Bustos Nahuel Bustos | Manchester CityMNC | → | São PauloSAO | Loan |
| 04 Aug 22 | S. Tedic Slobodan Tedic | Manchester CityMNC | → |  BarnsleyBAR | Loan |
| 04 Aug 22 | J. McAtee James McAtee | Manchester CityMNC | → |  Sheffield UnitedSHU | Loan |
| 02 Aug 22 | Y. Herrera Yangel Herrera | Manchester CityMNC | → |  GironaGIR | Loan |
| 29 Jul 22 | C. Slicker Cieran Slicker | Manchester CityMNC | → |  RochdaleRCH | Loan |
| 25 Jul 22 | D. Arzani Daniel Arzani | Manchester CityMNC | → |  Macarthur FCMAC | Free |
| 25 Jul 22 | Y. Couto Yan Couto | Manchester CityMNC | → | GironaGIR | Loan |
| 23 Jul 22 | O. Zinchenko Oleksandr Zinchenko | Manchester CityMNC | → |  ArsenalARS | Undisclosed |
| 22 Jul 22 | A. Muric Aro Muric | Manchester CityMNC | → |  BurnleyBUR | Undisclosed |
| 19 Jul 22 | Z. Steffen Zack Steffen | Manchester CityMNC | → |  MiddlesbroughMID | Loan |
| 16 Jul 22 | L. Fiorini Lewis Fiorini | Manchester CityMNC | → |  BlackpoolBLP | Loan |
| 13 Jul 22 | R. Sterling Raheem Sterling | Manchester CityMNC | → |  ChelseaCHE | Undisclosed |
| 11 Jul 22 | C. Doyle Callum Doyle | Manchester CityMNC | → |  Coventry CityCOV | Loan |
| 06 Jul 22 | R. Lavia Romeo Lavia | Manchester CityMNC | → | SouthamptonSOU | Undisclosed |
| 04 Jul 22 | D. Gyabi Darko Gyabi | Manchester CityMNC | → |  Leeds UnitedLEE | Undisclosed |
| 04 Jul 22 | T. Doyle Tommy Doyle | Manchester CityMNC | → | Sheffield UnitedSHU | Loan |
| 04 Jul 22 | K. Phillips Kalvin Phillips | Leeds UnitedLEE | → | Manchester CityMNC | Undisclosed |
| 04 Jul 22 | G. Jesus Gabriel Jesus | Manchester CityMNC | → | ArsenalARS | Undisclosed |
| 02 Jul 22 | K. Itakura Kou Itakura | Manchester CityMNC | → |  Borussia MonchengladbachBMG | Undisclosed |
| 01 Jul 22 | T. Harwood-Bellis Taylor Harwood-Bellis | Manchester CityMNC | → | BurnleyBUR | Loan |
| 01 Jul 22 | S. Ortega Stefan Ortega |  Arminia BielefeldDSC | → | Manchester CityMNC | Free |
| 01 Jul 22 | Fernandinho | Manchester CityMNC | → |  Athletico-PRCAP | Free |
| 01 Jul 22 | P. Porro Pedro Porro | Manchester CityMNC | → |  Sporting CPSCP | Undisclosed |
| 01 Jul 22 | J. Trafford James Trafford | Manchester CityMNC | → |  Bolton WanderersBOL | Loan |
| 01 Jul 22 | E. Haaland Erling Haaland | Borussia DortmundDOR | → | Manchester CityMNC | Undisclosed |
| 17 Jun 22 | G. Bazunu Gavin Bazunu | Manchester CityMNC | → | SouthamptonSOU | Undisclosed |
| 31 Jan 22 | S. Robinson Sam Robinson | Manchester CityMNC | → |  Port ValePTV | Undisclosed |
| 31 Jan 22 | J. Álvarez Julián Álvarez | Manchester CityMNC | → |  River PlateCARP | Loan |
| 31 Jan 22 | P. Sandler Philippe Sandler | Manchester CityMNC | → |  Feyenoord RotterdamFEY | Free |
| 31 Jan 22 | C. Gbadebo Camron Gbadebo | Manchester CityMNC | → |  Colchester UnitedCOL | Free |
| 31 Jan 22 | J. Álvarez Julián Álvarez | River PlateCARP | → | Manchester CityMNC | Undisclosed |
| 31 Jan 22 | E. Palmer-Brown Erik Palmer-Brown | Manchester CityMNC | → | TroyesTRY | Undisclosed |
| 31 Jan 22 | L. Bolton Luke Bolton | Manchester CityMNC | → |  Salford CitySAL | Undisclosed |
| 31 Jan 22 | M. Smith Matt Smith | Manchester CityMNC | → |  Milton Keynes DonsMKD | Undisclosed |
| 30 Jan 22 | L. Ilic Luka Ilic | Manchester CityMNC | → | TroyesTRY | Undisclosed |
| 30 Jan 22 | F. Burns Finley Burns | Manchester CityMNC | → |  Swansea CitySWA | Loan |
| 21 Jan 22 | P. Roberts Patrick Roberts | Manchester CityMNC | → |  SunderlandSUN | Undisclosed |
| 20 Jan 22 | T. Doyle Tommy Doyle | Manchester CityMNC | → |  Cardiff CityCAR | Loan |
| 13 Jan 22 | J. Trafford James Trafford | Manchester CityMNC | → | Bolton WanderersBOL | Loan |
| 11 Jan 22 | T. Harwood-Bellis Taylor Harwood-Bellis | Manchester CityMNC | → | Stoke CitySTK | Loan |
| 03 Jan 22 | F. Torres Ferran Torres | Manchester CityMNC | → |  BarcelonaBAR | Undisclosed |