| 25 Sept 22 | Allan |  EvertonEVE | → | AWXAl WahdaAl Wahda | Undisclosed |
| 20 Sept 22 | A. Kanuric Adnan Kanuric | XXX | → |  Nottingham ForestNFO | Free |
| 13 Sept 22 | E. Jakupovic Eldin Jakupovic | XXX | → | EvertonEVE | Free |
| 12 Sept 22 | L. Karius Loris Karius | XXX | → |  Newcastle UnitedNEW | Free |
| 12 Sept 22 | D. Costa Diego Costa | XXX | → |  Wolverhampton WanderersWOL | Free |
| 10 Sept 22 | A. Knockaert Anthony Knockaert |  FulhamFUL | → |  Volos NFCVOL | Loan |
| 08 Sept 22 | N. Redmond Nathan Redmond |  SouthamptonSOU | → |  BesiktasBES | Undisclosed |
| 07 Sept 22 | I. Cavaleiro Ivan Cavaleiro | FulhamFUL | → |  AlanyasporALA | Loan |
| 07 Sept 22 | S. Aurier Serge Aurier | XXX | → | Nottingham ForestNFO | Free |
| 02 Sept 22 | M. Batshuayi Michy Batshuayi |  ChelseaCHE | → |  FenerbahceFEN | Undisclosed |
| 01 Sept 22 | C. Marques Christian Marques | Wolverhampton WanderersWOL | → |  Forest Green RoversFGR | Loan |
| 01 Sept 22 | J. Wareham Jayden Wareham | ChelseaCHE | → |  Leyton OrientLEY | Loan |
| 01 Sept 22 | L. Warrington Lewis Warrington | EvertonEVE | → |  Fleetwood TownFLE | Loan |
| 01 Sept 22 | M. Woltman Max Woltman |  LiverpoolLIV | → |  Doncaster RoversDON | Loan |
| 01 Sept 22 | K. Watts Kelland Watts | Newcastle UnitedNEW | → |  Peterborough UnitedPET | Loan |
| 01 Sept 22 | H. Vale Harvey Vale | ChelseaCHE | → |  Hull CityHUL | Loan |
| 01 Sept 22 | B. Traore Boubacar Traore |  MetzMETZ | → | Wolverhampton WanderersWOL | Loan |
| 01 Sept 22 | R. Street Robert Street |  Crystal PalaceCRY | → |  Shrewsbury TownSHR | Loan |
| 01 Sept 22 | F. Stevens Finley Stevens |  BrentfordBRE | → |  Swansea CitySWA | Loan |
| 01 Sept 22 | D. Sterling Dujon Sterling | ChelseaCHE | → |  Stoke CitySTK | Loan |
| 01 Sept 22 | J. Stephens Jack Stephens | SouthamptonSOU | → |  AFC BournemouthBOU | Loan |
| 01 Sept 22 | J. Stansfield Jay Stansfield | FulhamFUL | → |  Exeter CityEXE | Loan |
| 01 Sept 22 | X. Simons Xavier Simons | ChelseaCHE | → | Hull CityHUL | Loan |
| 01 Sept 22 | D. Simeu Dynel Simeu | SouthamptonSOU | → |  Tranmere RoversTRN | Loan |
| 01 Sept 22 | C. Saydee Christian Saydee | AFC BournemouthBOU | → | Shrewsbury TownSHR | Loan |
| 01 Sept 22 | J. Olayinka James Olayinka |  ArsenalARS | → |  Cheltenham TownCHL | Loan |
| 01 Sept 22 | L. Mbete Luke Mbete |  Manchester CityMNC | → |  Huddersfield TownHUD | Loan |
| 01 Sept 22 | A. Maitland-Niles Ainsley Maitland-Niles | ArsenalARS | → | SouthamptonSOU | Loan |
| 01 Sept 22 | M. Longstaff Matthew Longstaff | Newcastle UnitedNEW | → |  Colchester UnitedCOL | Loan |
| 01 Sept 22 | M. Lis Mateusz Lis | SouthamptonSOU | → |  TroyesTRY | Loan |
| 01 Sept 22 | H. Lindley Hayden Lindley |  Aston VillaAVL | → |  Newport CountyNEW | Loan |
| 01 Sept 22 | Z. Larkeche Ziyad Larkeche | FulhamFUL | → |  BarnsleyBAR | Loan |
| 01 Sept 22 | L. Kurzawa Layvin Kurzawa |  Paris Saint-Germain PSG | → | FulhamFUL | Loan |
| 01 Sept 22 | T. Kongolo Terence Kongolo | FulhamFUL | → |  Le Havre ACHAC | Loan |
| 01 Sept 22 | S. Jasper Sylvester Jasper | FulhamFUL | → |  Bristol RoversBRI | Loan |
| 01 Sept 22 | D. James Daniel James |  Leeds UnitedLEE | → | FulhamFUL | Loan |
| 01 Sept 22 | T. Iroegbunam Tim Iroegbunam | Aston VillaAVL | → |  Queens Park RangersQPR | Loan |
| 01 Sept 22 | A. Gomes André Gomes | EvertonEVE | → |  LilleLILL | Loan |
| 01 Sept 22 | P. Glatzel Paul Glatzel | LiverpoolLIV | → | Tranmere RoversTRN | Loan |
| 01 Sept 22 | P. Gazzaniga Paulo Gazzaniga | FulhamFUL | → |  GironaGIR | Loan |
| 01 Sept 22 | E. Galbraith Ethan Galbraith |  Manchester UnitedMAN | → |  Salford CitySAL | Loan |
| 01 Sept 22 | W. Fish William Fish | Manchester UnitedMAN | → |  HibernianHIBS | Loan |
| 01 Sept 22 | B. Fiabema Bryan Fiabema | ChelseaCHE | → | Forest Green RoversFGR | Loan |
| 01 Sept 22 | M. Dúbravka Martin Dúbravka | Newcastle UnitedNEW | → | Manchester UnitedMAN | Loan |
| 01 Sept 22 | H. Dervisoglu Halil Dervisoglu | BrentfordBRE | → |  BurnleyBUR | Loan |
| 01 Sept 22 | C. Chukwuemeka Caleb Chukwuemeka | Aston VillaAVL | → |  Crawley TownCRA | Loan |
| 01 Sept 22 | J. Bowler Josh Bowler | Nottingham ForestNFO | → |  OlympiakosOLY | Loan |
| 01 Sept 22 | J. Bednarek Jan Bednarek | SouthamptonSOU | → | Aston VillaAVL | Loan |
| 01 Sept 22 | M. Bech Sörensen Mads Bech Sörensen | BrentfordBRE | → |  NiceNICE | Loan |
| 01 Sept 22 | E. Ampadu Ethan Ampadu | ChelseaCHE | → |  SpeziaSPE | Loan |
| 01 Sept 22 | Arthur |  JuventusJUV | → | LiverpoolLIV | Loan |
| 01 Sept 22 | H. Bellerín Héctor Bellerín | ArsenalARS | → |  BarcelonaBAR | Free |
| 01 Sept 22 | Willian | XXX | → | FulhamFUL | Free |
| 01 Sept 22 | C. Wright Callum Wright |  Leicester CityLEI | → |  BlackpoolBLP | Undisclosed |
| 01 Sept 22 | Y. Valery Yan Valery | SouthamptonSOU | → |  AngersANG | Undisclosed |
| 01 Sept 22 | B. Traore Boubacar Traore | MetzMETZ | → | Wolverhampton WanderersWOL | Undisclosed |
| 01 Sept 22 | O. Romeu Oriol Romeu | SouthamptonSOU | → | GironaGIR | Undisclosed |
| 01 Sept 22 | M. Moreno Marlos Moreno | Manchester CityMNC | → | TroyesTRY | Undisclosed |
| 01 Sept 22 | X. Mbuyamba Xavier Mbuyamba | ChelseaCHE | → |  FC VolendamVOL | Undisclosed |
| 01 Sept 22 | J. Larios Juan Larios | Manchester CityMNC | → | SouthamptonSOU | Undisclosed |
| 01 Sept 22 | W. Gnonto Wilfried Gnonto |  FC ZürichZUR | → | Leeds UnitedLEE | Undisclosed |
| 01 Sept 22 | B. Gilmour Billy Gilmour | ChelseaCHE | → |  Brighton & Hove AlbionBHA | Undisclosed |
| 01 Sept 22 | J. Garner James Garner | Manchester UnitedMAN | → | EvertonEVE | Undisclosed |
| 01 Sept 22 | F. Fernández Federico Fernández | Newcastle UnitedNEW | → |  ElcheELC | Undisclosed |
| 01 Sept 22 | W. Faes Wout Faes |  Stade de ReimsREIM | → | Leicester CityLEI | Undisclosed |
| 01 Sept 22 | Z. Emmerson Zac Emmerson | Brighton & Hove AlbionBHA | → | BlackpoolBLP | Undisclosed |
| 01 Sept 22 | S. Edozie Samuel Edozie | Manchester CityMNC | → | SouthamptonSOU | Undisclosed |
| 01 Sept 22 | L. Dendoncker Leander Dendoncker | Wolverhampton WanderersWOL | → | Aston VillaAVL | Undisclosed |
| 01 Sept 22 | T. Chong Tahith Chong | Manchester UnitedMAN | → |  Birmingham CityBIR | Undisclosed |
| 01 Sept 22 | D. Caleta-Car Duje Caleta-Car |  MarseilleOLM | → | SouthamptonSOU | Undisclosed |
| 01 Sept 22 | J. Bowler Josh Bowler | BlackpoolBLP | → | Nottingham ForestNFO | Undisclosed |
| 01 Sept 22 | W. Boly Willy Boly | Wolverhampton WanderersWOL | → | Nottingham ForestNFO | Undisclosed |
| 01 Sept 22 | L. Bade Loic Bade |  Stade RennaisREN | → | Nottingham ForestNFO | Undisclosed |
| 01 Sept 22 | M. Akanji Manuel Akanji |  Borussia DortmundDOR | → | Manchester CityMNC | Undisclosed |
| 01 Sept 22 | Kenedy | ChelseaCHE | → |  Real ValladolidVLL | Undisclosed |
| 01 Sept 22 | Carlos Vinicius |  BenficaBEN | → | FulhamFUL | Undisclosed |
| 01 Sept 22 | P. Aubameyang Pierre-Emerick Aubameyang | BarcelonaBAR | → | ChelseaCHE | 12000000 |
| 01 Sept 22 | D. Zakaria Denis Zakaria | JuventusJUV | → | ChelseaCHE | Loan |
| 01 Sept 22 | T. Wright Tyreik Wright | Aston VillaAVL | → |  Bradford CityBRD | Loan |
| 01 Sept 22 | I. Gueye Idrissa Gueye | Paris Saint-Germain PSG | → | EvertonEVE | Undisclosed |
| 01 Sept 22 | Antony |  Ajax AmsterdamAJA | → | Manchester UnitedMAN | 95000000 |
| 31 Aug 22 | A. El Ghazi Anwar El Ghazi | Aston VillaAVL | → |  PSV EindhovenPSV | Undisclosed |
| 31 Aug 22 | W. Fofana Wesley Fofana | Leicester CityLEI | → | ChelseaCHE | Undisclosed |
| 31 Aug 22 | S. Kalajdzic Sasa Kalajdzic |  VfB StuttgartVFB | → | Wolverhampton WanderersWOL | Undisclosed |
| 31 Aug 22 | Will Lankshear |  Sheffield UnitedSHU | → |  Tottenham HotspurTOT | Undisclosed |
| 31 Aug 22 | A. Palaversa Ante Palaversa | Manchester CityMNC | → | TroyesTRY | Undisclosed |
| 31 Aug 22 | O. Beck Owen Beck | LiverpoolLIV | → |  Bolton WanderersBOL | Loan |
| 31 Aug 22 | M. Bogusz Mateusz Bogusz | Leeds UnitedLEE | → |  UD IbizaIBI | Loan |
| 31 Aug 22 | J. Bryan Joe Bryan | FulhamFUL | → | NiceNICE | Loan |
| 31 Aug 22 | G. Hirst George Hirst | Leicester CityLEI | → |  Blackburn RoversBLK | Loan |
| 31 Aug 22 | A. Diallo Amad Diallo | Manchester UnitedMAN | → |  SunderlandSUN | Loan |
| 31 Aug 22 | T. Francois Tyrese Francois | FulhamFUL | → | HGXHNK GoricaHNK Gorica | Loan |
| 31 Aug 22 | A. Baba Abdul Rahman Baba | ChelseaCHE | → |  ReadingREA | Loan |
| 30 Aug 22 | S. Reguilón Sergio Reguilón | Tottenham HotspurTOT | → |  Atletico MadridATM | Loan |
| 30 Aug 22 | C. Romero Cristian Romero |  AtalantaATA | → | Tottenham HotspurTOT | Undisclosed |
| 30 Aug 22 | C. Hudson-Odoi Callum Hudson-Odoi | ChelseaCHE | → |  Bayer LeverkusenB04 | Loan |
| 30 Aug 22 | S. van den Berg Sepp van den Berg | LiverpoolLIV | → |  Schalke 04S04 | Loan |
| 30 Aug 22 | H. Winks Harry Winks | Tottenham HotspurTOT | → |  SampdoriaSAM | Loan |
| 30 Aug 22 | A. Okoflex Armstrong Okoflex |  West Ham UnitedWHU | → | Swansea CitySWA | Loan |
| 29 Aug 22 | L. Cundle Luke Cundle | Wolverhampton WanderersWOL | → | Swansea CitySWA | Loan |
| 29 Aug 22 | R. Lodi Renan Lodi | Atletico MadridATM | → | Nottingham ForestNFO | Loan |
| 29 Aug 22 | L. Paquetá Lucas Paquetá |  LyonLYON | → | West Ham UnitedWHU | Undisclosed |
| 29 Aug 22 | P. Cutrone Patrick Cutrone | Wolverhampton WanderersWOL | → |  ComoCOMO | Undisclosed |
| 29 Aug 22 | A. Mighten Alex Mighten | Nottingham ForestNFO | → |  Sheffield WednesdaySHW | Loan |
| 29 Aug 22 | H. Mejbri Hannibal Mejbri | Manchester UnitedMAN | → | Birmingham CityBIR | Loan |
| 27 Aug 22 | N. Nkounkou Niels Nkounkou | EvertonEVE | → |  Cardiff CityCAR | Loan |
| 27 Aug 22 | I. Poveda-Ocampo Ian Poveda-Ocampo | Leeds UnitedLEE | → | BlackpoolBLP | Loan |
| 26 Aug 22 | A. Isak Alexander Isak |  Real SociedadRSO | → | Newcastle UnitedNEW | Undisclosed |
| 26 Aug 22 | L. Plange Luke Plange | Crystal PalaceCRY | → | RMXRWD MolenbeekRWD Molenbeek | Loan |
| 26 Aug 22 | A. Odubeko Ademipo Odubeko | West Ham UnitedWHU | → |  Port ValePTV | Loan |
| 26 Aug 22 | J. O'Brien Jake O'Brien | Crystal PalaceCRY | → | RMXRWD MolenbeekRWD Molenbeek | Loan |
| 26 Aug 22 | J. Jenkins Jack Jenkins | Leeds UnitedLEE | → | Salford CitySAL | Loan |
| 26 Aug 22 | J. Gbamin Jean-Philippe Gbamin | EvertonEVE | → |  TrabzonsporTRAB | Loan |
| 26 Aug 22 | D. Chesters Daniel Chesters | West Ham UnitedWHU | → | |